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GET IT NOWThis butternut squash casserole was me throwing together random fall ingredients I had on hand, and it turned out to be the best decision. If you’ve been following along with me on Instagram, you know I’ve been looking to find new and different ways to use roasted butternut squash this season. I’m also big on cleaning out my fridge in a baking dish meal, and this one is just that — but also totally worth a store trip if you don’t have the ingredients around. My butternut squash casserole recipe is an irresistible combo of sweet, hearty autumn veggies and melty cheeses that capture the best of fall. Make it with me!
Why You Need My Butternut Squash Casserole Recipe

- Cozy fall flavors – This casserole packs all the best of fall into one dish. Cranberries! Butternut squash! Kale! Maple! It’s got all the cozy autumn flavors we all love this time of year.
- Easy to make – Some butternut squash casserole recipes are made similar to a sweet potato casserole, with a mashed filling and crunchy topping. This is more work though, and my recipe is easier — just roast, toss the ingredients together, and bake.
- Perfect for fall gatherings – This makes a wonderful Thanksgiving recipe for something different at your holiday table, but it’s also easy to prep ahead for a casual weeknight dinner.


Ingredients & Substitutions
Here I explain the best ingredients for my butternut squash casserole recipe, what each one does, and substitution options. For measurements, see the recipe card.
Roasted Squash & Onions:
Roasting them together is an easy way to cook them. The other ingredients help them get caramelized and flavorful:
- Butternut Squash – Peel and cut it into cubes. You could also roast acorn squash, delicata squash, or even kabocha squash for a slightly different flavor and texture.
- Onion – White, yellow, or red will work.
- Olive Oil – Or avocado oil.
- Maple Syrup – I add my natural Wholesome Yum Zero Sugar Maple Syrup for a touch of sweetness without the sugar. You could leave it out for a more savory butternut squash casserole — and you’ll still get a little sweetness from the cranberries (below). My husband prefers the savory version, while my kids and I love the hint of maple!
- Seasonings – Fresh thyme, garlic powder, salt, and pepper. If you don’t have thyme, rosemary or sage make great swaps! You can also use a teaspoon of dried herbs in place of the tablespoon of fresh.

Kale:
This is a simpler version of my sauteed kale recipe, and doesn’t add any extra time because you saute it while the squash roasts. You’ll need:
- Kale – I used curly kale, but lacinato kale or even spinach works. Removed the tough stems and chop into bite-sized pieces.
- Butter – Unsalted butter gives the kale extra flavor, but feel free to just use olive oil.
- Sea Salt & Black Pepper
VARIATION: Want extra garlic flavor?
Saute a few cloves of minced garlic together with the kale.

Assembly:
- Dried Cranberries – Make your own sugar-free dried cranberries, or store-bought is fine. When I don’t have time to make my own, I love these that are sweetened with only apple juice. You could also swap in raisins or dried cherries!
- Cheese – I used a mix of mozzarella and parmesan for a balance of melty and sharp. (If you’ve got lots, make my chicken fritters with them!) You can also swap the mozzarella for cheddar or gouda, and the parmesan for asiago or pecorino. You can even mix in goat cheese for a tangy flavor, kind of like my stuffed acorn squash.
VARIATION: Add some crunch!
If you like a little crunch, mix in some chopped pecans or walnuts into the bowl right before transferring to your casserole dish.

How To Make Butternut Squash Casserole
I have step-by-step photos here to help you visualize the recipe. For full instructions with amounts and temperatures, see the recipe card.
- Mix the squash and seasonings. In a large bowl, toss together the squash cubes, sliced onions, thyme, garlic powder, olive oil, maple syrup, salt, and pepper.
- Roast in the oven. Arrange the squash and onions on the baking sheet in a single layer. (Wipe down the bowl and set aside for later.) Roast, tossing halfway through, until the squash is fork tender and the onions start to caramelize.


- Saute the kale. Melt the butter in a Dutch oven over medium heat. Add the kale and saute, seasoning with salt and pepper as it wilts. Once it’s bright green, transfer to the large bowl.
- Add the squash and onions, cranberries, and cheeses. Mix them all together in the same large bowl. (Save half of the cheeses for topping.) Adjust salt and pepper if needed.


- Assemble the casserole. Pour the butternut squash mixture into a large baking dish. Sprinkle more shredded parmesan and mozzarella on top.
- Bake until melty. Place the butternut squash casserole in the oven and bake. If you want the cheese more browned, broil for a few minutes at the end.



My Recipe Tips
- To make the squash easier to peel, you can microwave it briefly. Just poke holes in the skin with a knife, then microwave for 2-3 minutes. This will soften the skin!
- Grab the largest bowl you’ve got for mixing. A whole squash plus a sliced onion take up a lot of space!
- Cut the squash into 3/4-inch cubes. If yours are larger, they will take longer to roast.
- I recommend a bare pan for roasting the squash and onions. Parchment paper makes for easier cleanup, but the squash and onions won’t caramelize as nicely. Foil would work fine, but make sure to spray with oil first to prevent sticking.
- Don’t crowd the sheet pan. You need a very large sheet pan (I use and love this one) to have enough space. Ideally, each piece should be touching the pan.
- A Dutch oven works best for sauteing the kale. 5 ounces is more than it sounds like! It cooks down a lot, but in the beginning the Dutch oven will be pretty full. You can use a very large skillet if you have to, but it’s harder to avoid losing pieces over the sides — you may need to cook in batches.
- You can adjust salt and pepper to taste. The best time to do this is in the bowl before transferring to a casserole dish. At this point you’ve already added the cheese, which is salty, and you’ll be able to taste how all the flavors work together.

Serving Ideas
My recipe for butternut squash casserole actually has enough protein to make a vegetarian (and gluten-free) meal if you like, but I usually serve it with a main dish. Here are some ideas:
- Main Dishes – Whip up my pan-fried chicken thighs, slow cook a pork tenderloin, or pop some turkey breast in the Crock Pot for a comforting fall meal.
- Sides – If you’re serving this butternut squash casserole as a main dish, it can definitely stand on its own, but you can add my almond flour biscuits or fall salad (which uses many of the same ingredients, yay!) to round out your dinner.
- Holiday Meal – My roasted turkey, beef tenderloin, or sirloin tip roast make flavorful holiday mains! Don’t forget the healthy green bean casserole, and of course sugar free cranberry sauce.
Butternut Squash Casserole
My easy butternut squash casserole is a cozy, cheesy blend of roasted squash, kale, onions, and cranberries. Perfect for fall and holidays!
Ingredients
Tap underlined ingredients to see the ones I use.
Roasted Squash & Onions:
Kale:
Assembly:
Instructions
Tap on the times in the instructions to start a kitchen timer.
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Preheat the oven to 400 degrees F (204 degrees C). Line an extra large baking sheet with parchment paper, or for better browning, leave it bare and spray with cooking spray.
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In a very large bowl, toss together the squash cubes, sliced onions, thyme, garlic powder, olive oil, maple syrup, salt, and pepper.
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Arrange the squash and onions on the baking sheet in a single layer. (Wipe down the bowl and set aside for later.)
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Roast the butternut squash and onions in the oven for 25-35 minutes, tossing halfway through, until the squash is fork tender. When done, leave the oven on.
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Meanwhile, melt the butter in a Dutch oven (or a very large skillet) over medium heat. Add the kale. Saute for 3-4 minutes, stirring occasionally, and season with salt and pepper as the kale wilts down. It’s done when it’s wilted and turns bright green. Transfer the kale to the large bowl you used earlier for the squash.
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When the squash and onions are done roasting, add them to the bowl with the kale. Add the dried cranberries, and half of both the mozzarella and parmesan cheeses (1/2 cup each). Toss to mix together. Adjust salt and pepper to your taste if needed.
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Transfer the mixture to a large baking dish. Sprinkle the remaining shredded parmesan and mozzarella (1/2 cup each) on top.
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Place the butternut squash casserole in the oven and bake for about 10 minutes, until the cheese is melted.
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If you want the cheese more browned, broil for 2-3 minutes, until golden.
LAST STEP: Leave a rating to help other readers, or tag me @wholesomeyum on Instagram. I’d love to hear from you!
Maya’s Recipe Notes
Serving size: 1 cup
- Tips: Check out my recipe tips above to make this dish easier for you to make! I’ve got an easier way to peel the squash, which pans and bowls to choose to avoid mishaps, and a few suggestions for flavor.
- Store: Keep leftovers in an airtight container in the fridge for up to 3-4 days.
- Meal prep: Roast the squash and onions, sauté the kale, and assemble everything in the dish. Pop it in the fridge until you’re ready to bake!
- Reheat: Bake at 350 degrees F for until warm, or microwave individual portions.
- Freeze: Wrap and freeze for up to 3 months. You can do this before or after the final baking step. Thaw before reheating, otherwise it takes forever!
- Nutrition note: This recipe uses sugar-free dried cranberries and sugar-free maple syrup. If you use regular ones, the sugar and carb content will be higher than shown below.
I provide nutrition facts as a courtesy. Have questions about calculations or why you got a different result? Please see my nutrition policy.
Add Your Notes Your Notes
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Butternut Squash Casserole

Gratitude Moment

After testing was over, I’ve made this butternut squash casserole 3 times this fall already! Which is saying a lot when I have a bunch of new recipes to test. 😉 It’s been so convenient to use up fall ingredients I always seem to have left after making other recipes. Plus, it’s an excuse for me to use my zero sugar maple syrup, which I always use more of in the fall.
Do you have go-to dishes you use to clean out your fridge this time of year? Let me know in the comments below!
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5 Comments
Lisa
0We made this for Solstice as I always try to make things with a nice bright golden color to represent the return of the sun. To be honest, I was thinking it would just be OK, but everybody absolutely loved it! I had never made a butternut recipe with cheese, and it was such a nice surprise. It was also a great compliment to the saffron chicken main dish.
Maya | Wholesome Yum
0What a fun idea, Lisa! Thank you for sharing. I’m so glad everyone enjoyed this butternut squash casserole recipe, and it sounds perfect with saffron chicken.
Gail
0This is my second time making this casserole, this time for company. It’s so rich in flavors and beautiful on the plate. Thank you for this nutritious and delicious recipe, Maya!
Gail
0My son cooked a chicken in the airfryer, while I made this casserole. We absolutely loved it.
I would cook the kale a bit longer the next time and add more thyme.
The flavors were so complimentary and the dish is so colorful that it would be perfect to serve guests. Will definitely be making this again soon. Thank you, Maya, for this delicious recipe.
Maya | Wholesome Yum
0I’m so glad everyone loved it, Gail! The time to cook the kale can vary a bit depending on your pan and the heat, feel free to adjust as needed. Enjoy!